Institut Charles Sadron Membre
Madeline Vauthier
- Téléphone : 03.88.41.40.00
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- MC
- Equipe : IP2
In 2015, Madeline Vauthier obtained her engineering diploma at the ECPM (Ecole européenne de Chimie, Polymères et Matériaux), University of Strasbourg and a M.Sc. degree in Material Sciences from the University of Strasbourg. During her M.Sc., she spent 6 months working in the Institut Charles Sadron (UPR22, University of Strasbourg) on the elaboration/design and characterization of multilayer films (polyelectrolytes & CaCO3 nanoparticles) using Layer-by-Layer technique under the supervision of Prof. Gero Decher and Dr. Olivier Felix.
She earned her Ph.D. degree in Material Chemistry (2018) from the University of Haute Alsace (UMR 7361, France) working under the direction of Prof. Vincent Roucoules and Dr. Florence Bally-Le Gall, where her thesis work dealt with the elaboration of smart coatings with interfacial thermoreversible properties. More precisely, the aim of this study was to design functional coatings (by post-functionalizing plasma polymers) that react via Diels-Alder chemistry, a thermoreversible reaction between a diene and a dienophile, and to understand their interfacial reactivity. A kinetics and thermodynamics methodology has then been developed to characterize thoroughly Diels-Alder interfacial reaction on coatings with various physico-chemical properties. The reversibility of this reaction under mild conditions was also investigated and outstanding results have been obtained without any alteration of the functional polymer coating even after five Diels-Alder / retro-Diels-Alder cycles. These results have led to the successful proof of concept of the reversible covalent adhesion between solid substrates.
She then worked one year (2018-2019) at Institut Charles Sadron as an ATER (temporary assistant professor) in the Precision Macromolecular Chemistry team, where she elaborated biocompatible, biodegradable stimuli-responsive polymeric nanoparticles.
In 2019, she permanently joined the Institut Charles Sadron as an assistant professor, teaching at the chemistry engineering school ECPM, and working on smart nano-objects .
RESEARCH INTEREST KEYWORDS
Polymer science, microfluidic systems, material chemistry, surface engineering, polymeric nanoparticles for targeted applications, polymersomes, encapsulation, stimuli-responsive polymers
CURRENT RESEARCH
In the team, we are interested in developing intensified polymer processes based on microreaction technology/microfluidic devices for the continuous-flow production of controlled-features polymeric micro- and nanoparticles. I am particularly interested in the functionalization of (bio)polymers or polymeric particles in order to control the systems' characteristics and morphologies (spheres, Janus, core-shell) only by changing the particles’ environment properties (= stimuli-responsive polymeric particles). Targeted applications include but not restricted to sensorics and theranostics.
TEAM MEMBERS
- Itab Youssef, ATER, 2023-2024
- Manissa Saïri, M2 student, 2024
- Vugar Khalilov, Ph.D. student, 2023-2026
- Andrea Acuña, IE (USIAS Fellowship 2023, ComPoClick), 2023-2025 https://www.usias.fr/fellows/fellows-2023/madeline-vauthier/
- Charlli Betkou, IE (CNRS pré-maturation ABBA), 2023-2024
- Esra Abdioglu, M2 student (INSERM PCSI ITMO cancer OSARM), 2023
- Hiba Hussein, IE (CNRS prématuration ABBA), 2022-2023
- Ismayil Safarli, M2 student (ITI HiFunMat project NanoHeatCAPs), 2022
- Javid Abdurahim, Ph.D. student, 2019-2022
- Andrea Acuña, M2 IMPolyS student, 2021
- Eirini Skoufa, Ph.D. student (ITN Marie Curie PHOTOEMULSION), 2018-2022
2023
Journal articles
- titre
- Elongational-flow elaboration of blend- and Janus-type polymeric nanoparticles
- auteur
- Javid Abdurahim, Christophe Serra, Madeline Vauthier
- article
- Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 675, pp.132062. ⟨10.1016/j.colsurfa.2023.132062⟩
- Resume_court
- Anisotropic particles, in shape or chemistry, have raised enthusiasm since they interact with their .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1016/j.colsurfa.2023.132062
- Accès au texte intégral et bibtex
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2022
Journal articles
- titre
- Controlled reversible aggregation of thermoresponsive polymeric nanoparticles by interfacial Diels-Alder reaction
- auteur
- Madeline Vauthier, Christophe Serra
- article
- Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 648, ⟨10.1016/j.colsurfa.2022.129321⟩
- Resume_court
- Hypothesis Stimuli-responsive polymers, with properties changing upon different environmental factor .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1016/j.colsurfa.2022.129321
- Accès au texte intégral et bibtex
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- titre
- One-step production of highly monodisperse size-controlled poly(lactic-co-glycolic acid) nanoparticles for the release of a hydrophobic model drug
- auteur
- Javid Abdurahim, Christophe Serra, Christian Blanck, Madeline Vauthier
- article
- Journal of Drug Delivery Science and Technology, 2022, 71, pp.103358. ⟨10.1016/j.jddst.2022.103358⟩
- Resume_court
- Biodegradable polymeric nanoparticles are considered as promising drug delivery systems due to their .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1016/j.jddst.2022.103358
- Accès au texte intégral et bibtex
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2021
Journal articles
- titre
- One-step elaboration of Janus polymeric nanoparticles: A comparative study of different emulsification processes
- auteur
- Madeline Vauthier, Marc Schmutz, Christophe Serra
- article
- Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 626, pp.127059. ⟨10.1016/j.colsurfa.2021.127059⟩
- Resume_court
- Hypothesis Janus polymeric nanoparticles have attracted much attention for their wide range of appli .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1016/j.colsurfa.2021.127059
- Accès au texte intégral et bibtex
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- titre
- One-step Production of Polyelectrolyte Nanoparticles
- auteur
- Madeline Vauthier, Christophe Alexandre Serra
- article
- Polymer international, 2021, Polymers for Defense, 70 (6), pp.860-865. ⟨10.1002/pi.6178⟩
- Resume_court
- Neutral polymeric nanoparticles have found many important applications in fields such as drug delive .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1002/pi.6178
- Accès au texte intégral et bibtex
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2020
Journal articles
- titre
- Design of Experience to Evaluate the Interfacial Compatibility on High Tenacity Viscose Fibers Reinforced Polyamide-6 Composites
- auteur
- Baptiste P. Revol, Madeline Vauthier, Matthieu Thomassey, Michel Bouquey, Frédéric Ruch, Michel Nardin
- article
- Composites Science and Technology, 2020, pp.108615. ⟨10.1016/j.compscitech.2020.108615⟩
- Resume_court
- In recent years, natural fibers reinforced composites have received much attention because of their .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1016/j.compscitech.2020.108615
- Accès au texte intégral et bibtex
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2019
Journal articles
- titre
- Interfacial Diels–Alder Reaction between Furan-Functionalized Polymer Coatings and Maleimide-Terminated Poly(ethylene glycol)
- auteur
- Madeline Vauthier, Loïc Jierry, Miguel Martinez Mendez, Yann-Matthieu Durst, Julien Kelber, Vincent Roucoules, Florence Bally-Le Gall
- article
- Journal of Physical Chemistry C, 2019, 123 (7), pp.4125-4132. ⟨10.1021/acs.jpcc.8b10533⟩
- Resume_court
- Surface functionalization is an interesting way to elaborate new smart materials. In this work, a tw .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1021/acs.jpcc.8b10533
- Accès au bibtex
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2018
Journal articles
- titre
- Interfacial Thermoreversible Chemistry on Functional Coatings: A Focus on the Diels–Alder Reaction
- auteur
- Madeline Vauthier, Loïc Jierry, Jamerson Carneiro Oliveira, Lilia Hassouna, Vincent V Roucoules, Florence Bally‐le Gall
- article
- Advanced Functional Materials, 2018, 29, pp.1806765. ⟨10.1002/adfm.201806765⟩
- Resume_court
- Stimuli-responsive materials have properties that depend on the environment in which they are used. .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1002/adfm.201806765
- Accès au bibtex
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- titre
- Control of Interfacial Diels–Alder Reactivity by Tuning the Plasma Polymer Properties
- auteur
- Madeline Vauthier, Loïc Jierry, Fouzia Boulmedais, Jamerson Oliveira, Kathryn Clancy, Chloé Simet, Vincent Roucoules, Florence Bally-Le Gall
- article
- Langmuir, 2018, 34 (40), pp.11960-11970. ⟨10.1021/acs.langmuir.8b02045⟩
- Resume_court
- Functionalizing the surface of a material with a smart plasma polymer coating is an interesting alte .....
- typdoc
- Journal articles
- DOI
- DOI : 10.1021/acs.langmuir.8b02045
- Accès au texte intégral et bibtex
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2023
Abdurahim, J.; Serra, C.A.; Vauthier, M. (2023), Elongational-flow elaboration of blend- and Janus-type polymeric nanoparticles,Colloids And Surfaces A-Physicochemical And Engineering Aspects,675() : link2022
Abdurahim, J.; Serra, C.A.; Blanck, C.; Vauthier, M. (2022), One-step production of highly monodisperse size-controlled poly (lactic-co-glycolic acid) nanoparticles for the release of a hydrophobic model drug,Journal Of Drug Delivery Science And Technology,71() : linkVauthier, M.; Serra, C.A. (2022), Controlled reversible aggregation of thermoresponsive polymeric nanoparticles by interfacial Diels-Alder reaction,Colloids And Surfaces A-Physicochemical And Engineering Aspects,648() : link
2021
Vauthier, M.; Schmutz, M.; Serra, C.A. (2021), One-step elaboration of Janus polymeric nanoparticles: A comparative study of different emulsification processes,Colloids And Surfaces A-Physicochemical And Engineering Aspects,626() : linkRevol, B.P.; Vauthier, M.; Thomassey, M.; Bouquey, M.; Ruch, F.; Nardin, M. (2021), Design of experience to evaluate the Interfacial compatibility on high tenacity viscose fibers reinforced Polyamide-6 composites,Composites Science And Technology,203() : link
Vauthier, M.; Serra, C.A. (2021), One-step production of polyelectrolyte nanoparticles,Polymer International,70(6, Si) : 860-865 link
2019
Vauthier, M.; Jierry, L.; Mendez, M.L.M.; Durst, Y.-M.; Kelber, J.; Roucoules, V.; Bally-Le Gall, F. (2019), Interfacial Diels-Alder Reaction between Furan-Functionalized Polymer Coatings and Maleimide-Terminated Poly(ethylene glycol),Journal Of Physical Chemistry C,123(7) : 4125-4132 linkVauthier, M.; Jierry, L.; Oliveira, J.C.; Hassouna, L.; Roucoules, V.; Bally-Le Gall, F. (2019), Interfacial Thermoreversible Chemistry on Functional Coatings: A Focus on the Diels-Alder Reaction,Advanced Functional Materials,29(10) : 1806765 link